The Papazion method outlined in his books talks of taking the alpha acids, multiplying by the ounces, and getting an HBU (Homebrewer Bittering Unit) number.
For example a recipe that calls for 2oz of 5.5 alpha hops is 11 HBUs, so you'd use 11/4.5 or 2.4 oz of your 4.5% alpha hops.
Personally, I just wing it. As an extreme IPA fan I have yet to use too much hops, and sometimes when I use less bittering than intended I just end up with more malt characteristics in the the glass.
If you keep experimenting and keep careful records you'll figure it out.
In the mean time you may accidentally stumble across a combination that you may have never seen in a recipe or thought of on your own, but really like and want to repeat.