I'm doing my first batch on the 25-gallon (kettle) Nano-brewer today.
http://cobrewingsystems.com/complete-pro-level-nano-brewer-down-under-single-vessel-brewing-system/ I think I have everything setup correctly for it...I hope. As for the 20-gallon Nano-brewer Home system, did you go to the downloads on their site and get the BeerSmith profile for it?
http://cobrewingsystems.com/downloads/ I used that as the basis for my equipment and then modified to the kettle and basket sizes. I'll have a better idea after today if the BeerSmith default BIAB absorption rate is accurate and how well I did along with getting an idea of what efficiency to expect. I'm targeting 80% on this brew.