Hi,
This is a known (but fairly rare) problem - and pretty easy to fix. Delete the "newopts14.opts" file from your C:\Program Files\BeerSmith directory and it should all come back just fine.
I also have a beta version patch that I believe fixes the problem but I'm trying to get a few more people to check it since I have been unable to duplicate the problem on my Vista machine. Just send me an email and I will send you a link to the patch.
Thanks,
Brad