upscaling to pro levels (15bbl)

[Blackthorn]

I'm in the planning stages of a 15bbl production brewery and I'm wondering if anyone is using BeerSmith on a professional level? 

[BeerSmith]

Yes,
  Quite a few do now - in fact Scott Hettig talked about using it on the BeerSmith podcast (#7).

  http://www.beersmith.com/blog/2011/01/14/beer-brewing-like-a-pro-bshb-podcast-7/

  The biggest difference when scaling a small batch up is the higher hop utilization you will get from a large microbrew system vice a small 5-10 gallon batch.  You will need less hops for the microbrewery.

Brad