My understanding of 5.2 Stabilizer is that it is a mixture of chemicals that have a lot of buffering capacity, which I think means it can "absorb" the change in pH that comes from the various inputs (water, minerals, grist). By design, a single product cannot predict every possible mash, so whether it would work for you may depend on your water, and the style beers you typically brew. But if your mash gets to ~5.2 pH, the stabilizer will help keep it there.
The desired pH range given for a mash is typically from 5.2 to 5.7 (or 5.5). The low end favors the alpha amylase and the high end favors the beta amylase, so one could use the pH to help reach the style desired. At the very least, one could try to make the pH NOT counter act the goal. If the goal is a big wee heavy or RIS, and the mash temp is 156F to favor the amylase and make more dextrins, then the mash pH goal should be 5.5 or 5.6, and not 5.2 or lower which favors beta.
The other consideration with mash chemicals is whether your local water supplies the calcium the yeast needs, and the relative balance of the other minerals to suit the styles you wish to brew. My local water has only 10 ppm calcium, so I always add some to reach >50 ppm, the recommended minimum for yeast performance. Since I've started using Palmer's water sheet, I've hit 5.25 to 5.35 mash pH every time.